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How are Targeted Cancer Therapies developed?

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Once a target has been identified, a therapy must be developed. Most targeted therapies are either small-molecule drugs or monoclonal antibodies. Small-molecule drugs are typically able to diffuse into cells and can act on targets that are found inside the cell. Most monoclonal antibodies usually cannot penetrate the cell’s plasma membrane and are directed against targets that are outside cells or on the cell surface.

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Departments Medical Oncology M.D. Prof. Necdet Üskent
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chemotherapy, genetic factors in cancer, targeted therapy, Necdet Üskent, Medical Oncology